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Confused. Cin 3.

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Confused. Cin 3.

I can't remember dates exactly but I had a smear last year that came back that I had tested positive for HPV and high grade (moderate) abnormal cells. I went for a colposcopy and the doctor did a biopsy (she later sent a letter saying she had done multiple biopsies and found cin 1 and 2). I then got a text to say I had an appointment. I hadn't recieved my results yet so rang them to be told I have cin 1 and 2. Went to the appointment in December to have the lletz done, at which point I was told by the doctor that unless the HPV goes, the precancerous cells will most likely keep coming back, she also tried to persuade me to not bother with the lletz and see if they go on their own as there is a chance they will. However I had already made the decision to have them removed and so she did that. After 8weeks I rang to get my results as I had not yet recieved them. And was told I have Cin 2 and Cin 3 and that I still have HPV. The lady told me it doesn't progress quickly and that they probably missed it the first time as they only take a small sample for biopsy and they only do one biopsy but I have the letter the doctor sent to my local gp saying she'd done multiple biopsies so how could they have missed it? Is that more likely than it progressing in less than 6months? I was given a new appointment for a 6month follow up smear for June but that was cancelled and now the hospital are not making any appointments for a while due to only taking Covid patients and emergencies. I'm starting to worry, how quickly can it progress to actual cancer? Everything I've read says it's unlikely but my results have really confused me. I've not really thought of it since I got the results but after being told that it could be the end of the year that they contact me for an appointment I'm freaking out a bit. Overthinking. I can't ring the helpline as I'm worried my children will hear and get worried so I guess I just needed to vent somewhere. If you got this far, I'm sorry it's such a long and pointless post, and thank you. 


It is not pointless and rambling! Your fears are well founded and it is scary. I am not trying to worry tou further but both times I had CIN III rhey immediately scheduled me for a Lietz. CIN III is not thought to regress on its own. 

Cervical cancer does grow slowly, but changes can happen quickly. I from a normal pap with HPV positive reading  to CIN III in a year, which my doctors have said is unusual. Then after that Lietz, i had two paps over 8 months that were CIN I. I waited six months and at rhe next pap had gone from CIN I to invasive cervical cancer, stage 1a1. My doctor was surprised and said thst does not usually happen, but I am proof that it can. I am going to be fine; radical hysterectomy was my cure, but CIN III is nothing to play around wirh.

if you are worried it would be worth making a call and seeing if you could get an appointment sooner than six months. Just my thoughts and onviously biased based on my situation, which could definitely be rare.

Best of luck!


11/18Abnormal Pap CINIII

12/18Colpo confirmsCINIII-horrible experience with cruel doctor

12/18Cold Knife cone biopsy confirms CiNIII, clear margins-doctor says we should just take it all out

1/19 second opinion-close monitoring appropriate

5/19, 8/19 paps and colpos CIN I

2/20 Pap reveals CIN III

3/17/20 Lietz under GA

3/20/20 Cervical Cancer, no clear margins- doctor calls my situation rare and shocking as my cone had clear margins

  1. 4/1/20-scan shows no evidence of spread Radical Hysterectomy, Lymph node dissection, and ovarian transposition May 12-pathhology staged cancer at 1a1. 


Jazza's picture

I haven't had a similar experience but, from everything I've read, anyone with cin3 cells should be prioritised.  It's not unknown for admin errors to occur which is possibly more likely in your case because you've had inconsistent results.  I think it is definitely worth chasing up and be sure to emphasise the cin3 part of your results to whoever you speak to.

Take care


  • Feb 04:  (age 47y) Smear test normal
  • Stopped going for smears!
  • Summer 16: persistent watery yellow vaginal discharge
  • Dec 16: post menopausal vaginal bleed
  • Jan 17: Hysteroscopy under GA for ?fibroids - abnormal cervix observed -multiple biopsies taken, 1B1  squamous  cell cc diagnosed - confirmed by MRI/PET scans
  • Feb 17: pelvic lymphadenectomy - nodes negative, Da Vinci radical hysterectomy- close anterior margin/LVSI/PNI, restaged to 2A
  • Apr/May 17: 6x chemo, 25x external radio, 2x brachy
  • May 20:  NED.  Various side effects notably hypotonic bladder since hysterectomy - ongoing ISC, unilateral lymphoedema lower abdo/groin/leg/ankle/foot

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Treatments for cervical cancer