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High grade smear but low grade biopsy

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Stacey Moore
High grade smear but low grade biopsy

Hi all, I had an abnormal smear result back in April, high grade severe dyskaryosis. Completely freaked out and worried myself sick. Had colposcopy just under 2 weeks later where I was told it actually looks low grade and could still have the treatment or have a biopsy I stead. Opted for biopsy, 3 samples taken. Results came back cin 1 which was great news bit they said it would be discussed at there meeting because of discrepancy between smear an biopsy. I went to drs because I have been having some bleeding an brown discharge after sex since biopsy ( bleeding after biopsy lasted a week then stoppes?) Dr looked at cervix an said it's coming from there an looks raw and then told me she had a letter saying hospital want me to have lletz after all to make sure the abnormal cells are not further up and after looking at my cervix said if it was her she would defo want it done. Now I'm worried all over again. Last Monday started with brown discharge again, by weds turned to blood an has been blood ever since like a period. I don't usually have periods as I'm on the pull. Has anyone experienced problems with bleeding this long after biopsy? Sorry for long post x



Hiya Stacey,

My smear came back the same but my biopsy showed moderate but in the end from my LLETZ it was CIN 3. LLETZ is a bigger sample so if you have this treatment the LLETZ should give you the definite result. 

I've had similar problems with bleeding but only after the LLETZ not the biopsy. 

Everyone is different and sometimes reading other stories you can diagnose yourself. Yes the not knowing is an awful experience but dwelling can make it seem worse. You're under the radar now so until you've had your LLETZ try to occupy your mind.


Good luck

Hugs x

  • 17th December smear results by post - high grade severe dyskaryosis

27th December punch biopsy, I was refused LLETZ treatment  due to heart condition so waiting for another appointment.

8th of January biopsy results - CIN 1 & 2  HPV positive strain 16.

LLETZ booked in for 21/3.

LLETZ under GA.

Waiting on results due in 4 weeks.

LLETZ results showed CIN 2 & 3 with clear margins.

09/11 Smear test of cure results. HPV NEGATIVE! Next smear test due 2022.


I have recently had the same, Smear CIN 3 and Biopsy 1/2. I'm going in for LLETZ Thursday and I am terrified it's going to be bad news and a different result.

Stacey - if you don't mind me asking did your LLETZ say anything different? 



Had similar discrepancy between smear & lletz biopsy results - due 3 month follow up coloposcopy in December - it's on my mind a lot

1st ever abnormal smear hpv & severe high grade dyskaryosis August 2019 lletz September 2019 polyp & nabothian cyst found Results hpv & mild cell changes polyp innocent Repeat colposcopy Dec 2019 test of cure January 2020 results of test of cure; no high risk HPV present , check up colposcopy appointment in June because of the discrepancy between initial smear & lletz result - June 2020 repeat colposcopy & pap - all clear - discharged from hospital - next smear in 3 yrs

More Information

Abnormal cervical cells and treatment

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