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I've recently completed my second round of treatment for VAIN/ VIN for abnormal cells in my upper vagina near my scar tissue following CIN treatment and a hysterectomy so this is more of a useful info update for anyone going through similar treatment.
This is my second treatment (one year later) as the first treatment did initially clear the cells but it returned again. However in positive news the imiquimod cream did keep the abnormal cells at bay for almost a year and reduced the systems which was continuous light bleeding and watery discharge.
The treatment both times was 6 weeks of having a tiny amount of cream applied in colposcopy twice a week as 1) the cream is pretty hardcore so you need the smallest amount and 2) I don't know about you but self applying a less than pea-sized amount of cream to the upper parts of the vagina to a precise spot is near impossible! So once again I am very grateful for the staff nurse team for doing this for me. They have been excellent. Turns out I'm only one of two women in my area having this treatment right now.
On imiquimod, applied internally it was more or less pain free. I always felt a bit weird afterwards but that seems to be having a colposcopy in general. According to the nurse there was some reddening and slight blistering towards the end and it felt a bit more sensitive each time.
As a treatment for me it has now cleared abnormal cells twice but I've yet to get past that one year all clear.
In terms of mental health, it has been easier this time too as I know it works to some extent, so at the very least it's keeping it at bay and I know longer have visible symptoms which was previously getting me down. So fingers crossed and if anyone is facing similar treatment please feel free to get in contact.
43, persistently CIN 3 now VAIN 3. No cervix and minus a womb.
2013 loop & Lletz
May 2014 1st cone biopsy
March 2015 2nd cone biopsy
Feb 2016 keyhole hysterectomy (kept ovaries)
March 2016 CIN3 found in cervix (now removed) awaiting a date for 6 month check up
Nov 2016 silver nitrate treatment for granulation
Dec 2016 confirmation of granulation all clear on biopsy
March 2017 laser, biopsy and a ovary scan
April 2017 Biopsy ok but now have VAIN
October 2017 2nd biopsy confirming VAIN 3
Dec 2017 lasered & biopsy
Jan/Mar 2018 start trial of Aldara Imiquimod
14 May next op examination