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Cervical cell changes (abnormal cells) may need treatment. Common treatments include LLETZ and cone biopsy.
We know being told you have cell changes that need treatment can be hard. We hope the information on this page helps prepare you and answers some questions. We also have information about:
Remember, our support services are here for you. Sometimes it can help to hear from someone who has been through a similar experience, so you may want to call our Helpline on 0808 802 8000 or join our Forum.
You may have treatment at your first colposcopy appointment. If you didn’t have it at your first colposcopy appointment, you should be invited for it within 4 to 6 weeks. Your colposcopist should be able to help with any questions about when you will have treatment.
Your treatment will depend on the type and grade of the cell changes. Common treatments for cell changes are:
Deciding on treatment can be a really personal thing, so before making decisions make sure you understand:
Your colposcopist should explain all of this. If they don’t, or you feel like you need more information, you can take the time to gather everything you need.
You may also feel emotionally affected by having treatment, whether that is relief, anxiety, confusion or a mix of these and more. All of your feelings, including any we don’t mention here, are valid. Many people feel this way and it’s important to get the support you need. Talking to your colposcopist may help.
We can also give you support, from chatting through how you’re feeling to answering general questions about cell changes and treatment.
LLETZ is the most common treatment for removing cell changes. It uses a thin wire loop with an electrical current to remove the area of the cervix where there are cell changes.
Your appointment will happen in the coloscopy clinic at a hospital. You are an outpatient, which means you can go home afterwards.
The hospital wants to keep you and your healthcare team protected from coronavirus, so they will be following government guidance on social distancing and using appropriate personal protective equipment (PPE).
Like during cervical screening (a smear test), your colposcopist will gently put a new, clean speculum into your vagina.
Your colposcopist will inject a local anaesthetic into your cervix. This means you are awake, but the area that needs treating is numb (you can’t feel it). The injection might sting for a short time.
Your colposcopist may also put a sticky pad on your leg. This makes sure the electric current doesn’t shock you or the colposcopist.
Once your cervix is numb, your colposcopist removes the area of the tissue with cell changes with the loop. It’s normal to notice a slight burning smell and hear a noise like a soft vacuum cleaner. The loop cuts the tissue and seals the cut at the same time. This should not be painful, but you may feel some pressure.
The removed area is sent to a laboratory to test:
If you have cell changes inside your cervical canal (CGIN), you may need a deeper treatment to diagnose and remove abnormal cells there. You may be offered:
SWETZ and NETZ are similar to LLETZ, but the thin wire is straight, rather than a loop. Depending on the results and your situation, you may need another excision or be offered a hysterectomy. If this happens, your colposcopist will talk through all the options with you.
A cone biopsy is a small surgery that will remove a cone-shaped piece of tissue from your cervix.
A cone biopsy is done under general anaesthetic, which means you are asleep and won’t feel anything. The treatment takes about 15 minutes. Afterwards, you may have to stay in hospital overnight.
A cone biopsy can be done with a:
After a cone biopsy, your doctor may put a small pack of gauze (like a tampon) in your vagina to stop bleeding. You may also have a tube (a catheter) to drain urine from the bladder while the gauze pack is in place. The gauze and tube are usually removed within 8 hours. Once they have been removed, you can go home.
The cone-shaped piece of tissue is sent to a laboratory to test:
Other treatments for cell changes include:
Before any of these treatments, you will usually have a local anaesthetic. This means you are awake, but the area that needs treating is numb so you can’t feel it. The injection might sting for a short time.
These treatments are not used as often. You have them as an outpatient, which means you have them in hospital, but can go home afterwards.
After treatment for cell changes, you may have some common side effects. We all react and heal differently after treatment, so you may not experience these effects exactly as we describe.
Having treatment can affect your emotional wellbeing, as well as your body. After treatment, you may be worried about:
All your concerns, including any we don’t mention here, are valid. Many people feel this way and it’s important you get the support you need. You can talk to your colposcopist about any worries you have, as well as to us.
Some people have cramping pain, like a period, after treatment. The pain varies from person to person, but some pain is expected for a couple of days after treatment.
If you are in a lot of pain or find it is affecting your day-to-day life, speak with your colposcopist or GP. They can offer reassurance based on your medical history and, if needed, will be able to check you are healing properly.
After treatment, a soft scab forms on the cervix where the cells were removed. While this heals, it may cause bleeding and changes to vaginal discharge. This can last about 4 weeks.
Any bleeding is usually like a slightly heavy period. About 10 days after treatment, the bleeding may get heavier. This is very normal and simply the soft scab healing.
If the bleeding is very heavy and you are soaking through a sanitary pad every few hours, it is important you go to the hospital straight away. It may not be anything to worry about, but they can check everything is okay and offer the right care.
Your first period (monthly bleeding) after treatment may be slightly heavier or out-of-sync with your regular cycle.
Straight after treatment, you may have a watery vaginal discharge, and about 10 days after treatment, many women notice a coffee granule-like vaginal discharge. This is very normal and simply the soft scab healing.
Speak with your GP if your vaginal discharge:
If you have an infection, your GP may give you antibiotics.
Until any bleeding has stopped and vaginal discharge has gone back to normal, your colposcopist may advise you not to:
If you are unsure what you should or shouldn’t do, ask your colposcopist or GP.
Treatments for cell changes are considered safe. They are treatments that have been approved by health organisations in the UK and are usually successful.
However, as with all treatments, there are some possible risks.
After LLETZ or cone biopsy, there is a small chance that the cervix will narrow. If this happens, the passage between the womb and vagina can become partly or fully blocked. This is called cervical stenosis.
Cervical stenosis is more likely if:
If you are worried about cervical stenosis or think you may have it, speak with your colposcopist or GP. They can offer support and practical ways to help, like using a thin tube (dilator) with lubricant to help open the cervix.
After LLETZ or cone biopsy, there is a slightly increased risk of miscarriage and giving birth before 37 weeks (prematurely).
At first, this can sound alarming, but it’s important we try to understand exactly what is meant by this increased risk. In real numbers, after treatment about 2 in every 100 women will give birth prematurely. When we talk about premature births, in most cases we are talking about births between 32 and 37 weeks – so not severely premature.
The level of risk will depend on:
However, the following is accepted:
Most LLETZ and cone biopsy treatments remove less than 10mm of cervical tissue.
If you are planning on having children, it can be really worrying to read about these slight increased risks. It may help to remember that your healthcare team – both before and during any pregnancy – are there to support you and make sure you have the right care. You may want to speak with your colposcopist before treatment about any concerns, so they can answer your questions and give you support.
If you get pregnant in future, it is important to tell your midwife that you have had LLETZ. They may offer to do an ultrasound scan of your cervix. If they think it is short and there is a risk you may have the baby a bit early, they may offer you a cervical stitch (cervical cerclage). This is an operation where a stitch is placed around the cervix. It is usually done between 12 and 24 weeks of pregnancy, although it may be done later.
If you are worried, it may help to speak with your colposcopist or midwife. They will be able to answer your questions and offer any support you need.
Treatment is successful for about 9 in 10 people. It can be really upsetting if the treatment doesn’t work or if cell changes come back but, just like before, you will have an expert team caring for you.
Even though cell changes like CIN and CGIN aren’t cervical cancer, you are sometimes offered treatment to reduce the risk of developing cervical cancer in the future.
After LLETZ, it is important to listen to your body and take any time you need to rest. We all heal at different rates, so what feels right for someone else may not be right for you.
You can exercise as soon as you feel ready. Remember, any side effects usually last for about 4 weeks, so you may want to avoid heavy exercise during that time. If you do exercise, any bleeding may be a little heavier afterward.
If you have any worries or want to ask about a specific exercise, you can speak with your colposcopist before LLETZ. Or you can ask your GP, who knows your full medical history.
After LLETZ, side effects can last for about 4 weeks, so it is best not to have penetrative vaginal sex. This includes:
The general rule is don’t put anything in your vagina while you have any side effects. If you want to have anal sex or clitoral stimulation, this shouldn’t make any side effects worse.
If you are worried or have specific questions, it is best to speak to your colposcopist before treatment. Or you could speak to your GP, who knows your full medical history.
If you have a holiday planned soon after your treatment, speak with your colposcopist beforehand. They may recommend you don’t fly until any side effects have stopped – these may last for about 4 weeks.
As well as leaning on your colposcopist, we are here for you. Our services are open if you want to talk through anything or simply have someone listen to your concerns on 0808 802 8000.
We also have a welcoming community in our online Forum, where you can get and give support. There are lots of conversations about cell changes, so you can choose to read existing threads or post your own messages.
If you have general questions about cell changes or treatment, our Ask the Expert service may be able to help. Submit your question confidentially to our panel of experts and get a tailored reply.
Thank you to all the experts who checked the accuracy of this information, and the volunteers who shared their personal experience to help us develop it.
We write our information based on literature searches and expert review. For more information about the references we used, please contact [email protected]